Data-driven prediction of adverse drug reactions induced by drug-drug interactions

Cutaneous adverse drug reactions induced by Oxcarbazepine

Poster background Oxcarbazepine (OXC) is a structural analog of carbamazepine (CBZ). OXC is considered a promising alternative medication for patients who cannot tolerate CBZ because of its equivalent clinical effiecacy and fewer cutaneous adverse drug reactions (cADRs) compared to CBZ. HLAB*15:02 allele was shown to strongly associate with carbamazepine (CBZ)-induced Stevens-Johnson syndrome (...

adverse cutaneous drug reactions

-----------

Adverse drug reactions to antibiotics and major antibiotic drug interactions.

Adverse drug reaction and drug interactions represent negative consequences of pharmacotherapy. A thorough knowledge of how the adverse reactions and drug interactions occur will aid in our ability to provide the best patient care possible. Adverse drug reactions and drug interactions are defined and mechanisms of their occurrence are discussed; ways to identify, assess, manage, and report thes...

Antibiotic adverse reactions and drug interactions.

When contemplating antibiotic use, intensivists must consider possible beneficial and harmful drug interactions. After antibiotics are instituted, adverse reactions must be anticipated. Acute illness, comorbidities, and concurrent medications affect the presentation and management of antibiotic-related adverse events. Intensivists should use the fewest possible antibiotics, carefully choosing a...

the evaluation of isotretinoin induced adverse drug reactions